Director, Molecular Science

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com. The mission of the Innovation Lab is to increase the diagnostic yield of our exome and genome products and reduce the time to diagnosis for patients with an undiagnosed hereditary disease. The big goal is to deliver personalized and actionable health insights to every person who orders a genetic test from GeneDx. Achievement of our goals will require a culture of innovation, where creativity, experimentation, and the pursuit of new ideas are encouraged and embraced. Individuals are empowered to think critically, take risks, and challenge the status quo, to generate breakthrough solutions and drive positive change. Summary: We are seeking an accomplished and creative Director of Molecular Science to lead molecular research and innovation initiatives. This role is responsible for overseeing the design, execution, and strategic direction of molecular biology programs, including genomics, proteomics, gene editing, and biomarker discovery. The ideal candidate will bring deep scientific expertise, strong leadership, product development experience, and a passion for advancing molecular science and genomic testing. Job Responsibilities: • Initiate, lead, and manage molecular science research programs designed to improve diagnostic testing for rare diseases. • Oversee the design and execution of experiments involving DNA/RNA technologies, gene expression, CRISPR, sequencing, and molecular diagnostics. • Ensure scientific rigor, data integrity, and compliance with regulatory and ethical standards. • Collaborate with cross-functional teams, including laboratory innovation, bioinformatics, translational genetics, biostatistics, clinical research, regulatory affairs, and product development. • Evaluate and integrate emerging molecular technologies and platforms, including DNA/RNA sequencing, proteomics, functional genomics and cytogenetics. • Mentor and develop scientific staff, fostering a culture of innovation, collaboration, and continuous learning. • Represent the organization in scientific forums and research collaborations. • Manage budgets, timelines, and resource allocation for molecular science initiatives. People Manager: • No Education, Experience, and Skills: • D. in Molecular Biology, Genetics, Biochemistry, or a related field. • 10+ years of experience in molecular research, with at least 5 years in a leadership role. • Proven track record of scientific innovation, publications, and/or patents in molecular science. • Expertise in molecular techniques such as PCR, qPCR, NGS, gene editing, and molecular diagnostics. • Strong leadership, communication, and project management skills. • Experience in regulated environments (e.g., GLP, CLIA, FDA) is a plus. Certificates, Licenses, Registrations: N/A Physical Demands: • Ability to stand, walk, and sit for extended periods. Work Environment: • Fully Remote Acknowledgements The above job description is not intended to be an all-inclusive list of duties and standards of the position. Incumbents will follow any other instructions, and perform any other related duties, as assigned by their supervisor. #LI-REMOTE Pay Transparency, Budgeted Range $183,664—$229,580 USD ~ Science - Minded, Patient - Focused. At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care. Experts in what matters most. With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust. SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES. From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way: TECHNICAL EXPERTISE • High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved. • Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed. CLINICAL EXPERTISE • Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence. • Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations. • Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals. Learn more About Us here. Our Culture At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by: • Be bold in our vision & brave in our execution. • Communicate directly, with empathy. • Do what we say we're going to do. • Be adaptable to change. • Operate with a bias for action. Benefits include: • Paid Time Off (PTO) • Health, Dental, Vision and Life insurance • 401k Retirement Savings Plan • Employee Discounts • Voluntary benefits GeneDx is an Equal Opportunity Employer. All privacy policy information can be found here.